Research

Below is a list of studies and research referenced throughout our website and within our downloads.

 

Medications—including anticonvulsants, muscle relaxants, and tricyclic antidepressants—will relieve the pain in roughly 75% of patients.

 

Outcomes for Radiosurgery: 80–85% cure with at least 25% recurrence

 

Outcomes for Percutaneous Rhizotomy: 90–95% cure with 20–25% recurrence

 

Outcomes for Microvascular Decompression (MVD): 90–95% cure with 20–25% recurrence

 

Ideal Candidate for Microvascular Decompression (MVD): Many patients of all ages with limited anesthesia risk; MVD for TN is a safe procedure even in the elderly; the risk of serious morbidity or mortality is similar to that in younger patients

 

In cases of particularly intractable trigeminal neuralgia, multiple surgical treatments—which can be attempted in any order—may be necessary. Although scarring from radiosurgery was once believed to prevent the use of other surgical techniques, it has since been found this is not the case. MVD is occasionally repeated, especially after long periods of relief; a Mayo Clinic study found that radiosurgery provided adequate pain relief to 80% of patients when it was repeated. (In other words, radiosurgery relieves pain in 80 out of 100 TN patients. If the remaining 20 patients were given a subsequent round of radiosurgery, 16 of those patients—or 80%—would gain relief.) PRR can be utilized multiple times.  Occasionally, partial cutting of the nerve (partial sensory rhizotomy, or PSR) is necessary when multiple other attempts have failed.